Creative Coding

Recently, a friend and I decided to collaborate on some creative coding projects. But of us stare at computers most of the day (this is my friend). These projects are not work-related, but they do have the goal of helping us learn some coding tool we’re trying to master.

Balancing Selection: methods, signatures, mechanisms

Balancing selection is an umbrella turn for several evolutionary mechanisms through which adaptive variation is maintained in populations. While it is often understood as simply overdominance or heterozygote advantage, it encompasses not only that mechanism, but also antagonistic selection, fluctuating selection in time/space, negative frequency dependent selection, to name a few.

What drives the reduced prediction accuracy of polygenic scores in non-European individuals?

Investigations on different methods for PRS calculation, the effects of different modelling and pruning approeches, and transferability of PRS across ancestries